INFLAMMATION OF VEINS.

Biomarkers of low-grade inflammation in primary varicose veins of the lower limbs.

OBJECTIVE To analyze serum biomarkers of CVD in selected patients with primary axial reflux of great saphenous vein in one or both lower limbs. PATIENTS AND METHODS Ninety-six patients affected by uncomplicated varicose veins, were enrolled in the study. A unilateral, primary axial reflux in great saphenous veins was detected in 54 patients (U-CVD group) and a bilateral one in 42 (B-CVD group...

Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice

An alternative hypothesis has been proposed implicating chronic cerebrospinal venous insufficiency (CCSVI) as a potential cause of multiple sclerosis (MS). We aimed to evaluate the validity of this hypothesis in a controlled animal model. Animal experiments were approved by the institutional animal care committee. The jugular veins in SJL mice were ligated bilaterally (n = 20), and the mice wer...

A study of various occurrences of the Al2SiO5 polymorphs in the rocks/veins of the Hamedan region, Iran: with special reference to origin of quartz-kyanite veins

The study area is a part of so-called Sanandaj-Sirjan zone or Zagros imbricate zone of the Zagros Orogen, Iran. The Hamedan region comprises a metamorphic sequence of low- to high-grade regional and contact metamorphic rocks intruded by mafic, intermediate and felsic plutonic bodies. The sequence comprises pelitic, psammitic, mafic, calc-pelitic and calc-silicate rocks.  Pelitic rocks are the m...

Varicose Veins

Management of varicose veins.

Varicose veins are twisted, dilated veins most commonly located on the lower extremities. Risk factors include chronic cough, constipation, family history of venous disease, female sex, obesity, older age, pregnancy, and prolonged standing. The exact pathophysiology is debated, but it involves a genetic predisposition, incompetent valves, weakened vascular walls, and increased intravenous press...